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Regularized regression method for genome-wide association studies

We use a novel penalized approach for genome-wide association study that accounts for the linkage disequilibrium between adjacent markers. This method uses a penalty on the difference of the genetic effect at adjacent single-nucleotide polymorphisms and combines it with the minimax concave penalty,...

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Detalles Bibliográficos
Autores principales:	Liu, Jin, Wang, Kai, Ma, Shuangge, Huang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287906/ https://www.ncbi.nlm.nih.gov/pubmed/22373491 http://dx.doi.org/10.1186/1753-6561-5-S9-S67

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