Detecting disease rare alleles using single SNPs in families and haplotyping in unrelated subjects from the Genetic Analysis Workshop 17 data

We present an evaluation of discovery power for two association tests that work well with common alleles but are applied to the Genetic Analysis Workshop 17 simulations with rare causative single-nucleotide polymorphisms (SNPs) (minor allele frequency [MAF] < 1%). The methods used were genome-wid...

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Detalles Bibliográficos
Autores principales: Kraja, Aldi T, Czajkowski, Jacek, Feitosa, Mary F, Borecki, Ingrid B, Province, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287938/
https://www.ncbi.nlm.nih.gov/pubmed/22373254
http://dx.doi.org/10.1186/1753-6561-5-S9-S96

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