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Polymorphisms of the pfmdr1 but not the pfnhe-1 gene is associated with in vitro quinine sensitivity in Thai isolates of Plasmodium falciparum
BACKGROUND: The emergence of Plasmodium falciparum resistance to most currently used anti-malarial drugs is a major problem in malaria control along the Thai-Myanmar and Thai-Cambodia borders. Quinine (QN) with tetracycline/doxycycline has been used as the second-line treatment for uncomplicated fal...
Autores principales: | Poyomtip, Teera, Suwandittakul, Nantana, Sitthichot, Narumon, Khositnithikul, Rommanee, Tan-ariya, Peerapan, Mungthin, Mathirut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287963/ https://www.ncbi.nlm.nih.gov/pubmed/22221394 http://dx.doi.org/10.1186/1475-2875-11-7 |
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