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Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex

Spectral integration properties show topographical order in cat primary auditory cortex (AI). Along the iso-frequency domain, regions with predominantly narrowly tuned (NT) neurons are segregated from regions with more broadly tuned (BT) neurons, forming distinct processing modules. Despite their pr...

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Detalles Bibliográficos
Autores principales: Atencio, Craig A., Schreiner, Christoph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288040/
https://www.ncbi.nlm.nih.gov/pubmed/22384036
http://dx.doi.org/10.1371/journal.pone.0031537
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author Atencio, Craig A.
Schreiner, Christoph E.
author_facet Atencio, Craig A.
Schreiner, Christoph E.
author_sort Atencio, Craig A.
collection PubMed
description Spectral integration properties show topographical order in cat primary auditory cortex (AI). Along the iso-frequency domain, regions with predominantly narrowly tuned (NT) neurons are segregated from regions with more broadly tuned (BT) neurons, forming distinct processing modules. Despite their prominent spatial segregation, spectrotemporal processing has not been compared for these regions. We identified these NT and BT regions with broad-band ripple stimuli and characterized processing differences between them using both spectrotemporal receptive fields (STRFs) and nonlinear stimulus/firing rate transformations. The durations of STRF excitatory and inhibitory subfields were shorter and the best temporal modulation frequencies were higher for BT neurons than for NT neurons. For NT neurons, the bandwidth of excitatory and inhibitory subfields was matched, whereas for BT neurons it was not. Phase locking and feature selectivity were higher for NT neurons. Properties of the nonlinearities showed only slight differences across the bandwidth modules. These results indicate fundamental differences in spectrotemporal preferences - and thus distinct physiological functions - for neurons in BT and NT spectral integration modules. However, some global processing aspects, such as spectrotemporal interactions and nonlinear input/output behavior, appear to be similar for both neuronal subgroups. The findings suggest that spectral integration modules in AI differ in what specific stimulus aspects are processed, but they are similar in the manner in which stimulus information is processed.
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spelling pubmed-32880402012-03-01 Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex Atencio, Craig A. Schreiner, Christoph E. PLoS One Research Article Spectral integration properties show topographical order in cat primary auditory cortex (AI). Along the iso-frequency domain, regions with predominantly narrowly tuned (NT) neurons are segregated from regions with more broadly tuned (BT) neurons, forming distinct processing modules. Despite their prominent spatial segregation, spectrotemporal processing has not been compared for these regions. We identified these NT and BT regions with broad-band ripple stimuli and characterized processing differences between them using both spectrotemporal receptive fields (STRFs) and nonlinear stimulus/firing rate transformations. The durations of STRF excitatory and inhibitory subfields were shorter and the best temporal modulation frequencies were higher for BT neurons than for NT neurons. For NT neurons, the bandwidth of excitatory and inhibitory subfields was matched, whereas for BT neurons it was not. Phase locking and feature selectivity were higher for NT neurons. Properties of the nonlinearities showed only slight differences across the bandwidth modules. These results indicate fundamental differences in spectrotemporal preferences - and thus distinct physiological functions - for neurons in BT and NT spectral integration modules. However, some global processing aspects, such as spectrotemporal interactions and nonlinear input/output behavior, appear to be similar for both neuronal subgroups. The findings suggest that spectral integration modules in AI differ in what specific stimulus aspects are processed, but they are similar in the manner in which stimulus information is processed. Public Library of Science 2012-02-27 /pmc/articles/PMC3288040/ /pubmed/22384036 http://dx.doi.org/10.1371/journal.pone.0031537 Text en Atencio, Schreiner. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Atencio, Craig A.
Schreiner, Christoph E.
Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
title Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
title_full Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
title_fullStr Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
title_full_unstemmed Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
title_short Spectrotemporal Processing in Spectral Tuning Modules of Cat Primary Auditory Cortex
title_sort spectrotemporal processing in spectral tuning modules of cat primary auditory cortex
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288040/
https://www.ncbi.nlm.nih.gov/pubmed/22384036
http://dx.doi.org/10.1371/journal.pone.0031537
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