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Trastuzumab Produces Therapeutic Actions by Upregulating miR-26a and miR-30b in Breast Cancer Cells

OBJECTIVE: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be beneficial to improve the treatment of HER2-positive BC...

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Detalles Bibliográficos
Autores principales:	Ichikawa, Takehiro, Sato, Fumiaki, Terasawa, Kazuya, Tsuchiya, Soken, Toi, Masakazu, Tsujimoto, Gozoh, Shimizu, Kazuharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288043/ https://www.ncbi.nlm.nih.gov/pubmed/22384020 http://dx.doi.org/10.1371/journal.pone.0031422

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