Structural and Functional Analysis of Validoxylamine A 7′-phosphate Synthase ValL Involved in Validamycin A Biosynthesis

Validamycin A (Val-A) is an effective antifungal agent widely used in Asian countries as crop protectant. Validoxylamine A, the core structure and intermediate of Val-A, consists of two C(7)-cyclitol units connected by a rare C-N bond. In the Val-A biosynthetic gene cluster in Streptomyces hygroscop...

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Detalles Bibliográficos
Autores principales: Zheng, Lina, Zhou, Xiang, Zhang, Huaidong, Ji, Xiaofeng, Li, Lei, Huang, Lin, Bai, Linquan, Zhang, Houjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288074/
https://www.ncbi.nlm.nih.gov/pubmed/22384130
http://dx.doi.org/10.1371/journal.pone.0032033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288074/
https://www.ncbi.nlm.nih.gov/pubmed/22384130
http://dx.doi.org/10.1371/journal.pone.0032033

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