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MCP1 SNPs and Pulmonary Tuberculosis in Cohorts from West Africa, the USA and Argentina: Lack of Association or Epistasis with IL12B Polymorphisms

The monocyte chemotactic protein-1 (MCP-1) is a chemokine that plays an important role in the recruitment of monocytes to M. tuberculosis infection sites, and previous studies have reported that genetic variants in MCP1 are associated with differential susceptibility to pulmonary tuberculosis (PTB)....

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Detalles Bibliográficos
Autores principales: Velez Edwards, Digna R., Tacconelli, Alessandra, Wejse, Christian, Hill, Philip C., Morris, Gerard A. J., Edwards, Todd L., Gilbert, John R., Myers, Jamie L., Park, Yo Son, Stryjewski, Martin E., Abbate, Eduardo, Estevan, Rosa, Rabna, Paulo, Novelli, Giuseppe, Hamilton, Carol D., Adegbola, Richard, Østergaard, Lars, Williams, Scott M., Scott, William K., Sirugo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288089/
https://www.ncbi.nlm.nih.gov/pubmed/22384203
http://dx.doi.org/10.1371/journal.pone.0032275