Cargando…

Mouse Background Strain Profoundly Influences Paneth Cell Function and Intestinal Microbial Composition

BACKGROUND: Increasing evidence supports the central role of Paneth cells in maintaining intestinal host-microbial homeostasis. However, the direct impact of host genotype on Paneth cell function remains unclear. Here, we characterize key differences in Paneth cell function and intestinal microbial...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gulati, Ajay S., Shanahan, Michael T., Arthur, Janelle C., Grossniklaus, Emily, von Furstenberg, Richard J., Kreuk, Lieselotte, Henning, Susan J., Jobin, Christian, Sartor, R. Balfour
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288091/ https://www.ncbi.nlm.nih.gov/pubmed/22384242 http://dx.doi.org/10.1371/journal.pone.0032403

Ejemplares similares

Mouse Paneth cell antimicrobial function is independent of Nod2
por: Shanahan, Michael T, et al.
Publicado: (2014)

Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice
por: Rogala, Allison R., et al.
Publicado: (2018)

PANETH CELL GRANULE OF MOUSE INTESTINE
por: Selzman, H. M., et al.
Publicado: (1962)

Paneth cells in intestinal physiology and pathophysiology
por: Gassler, Nikolaus
Publicado: (2017)

Paneth cells as a site of origin for intestinal inflammation
por: Adolph, Timon E., et al.
Publicado: (2013)

Paneth Cells in Intestinal Homeostasis and Tissue Injury
por: Roth, Sabrina, et al.
Publicado: (2012)

The Paneth Cell: The Curator and Defender of the Immature Small Intestine
por: Lueschow, Shiloh R., et al.
Publicado: (2020)

Secretory Sorcery: Paneth Cell Control of Intestinal Repair and Homeostasis
por: Cray, Paul, et al.
Publicado: (2021)

Paneth cells as the origin of intestinal cancer in the context of inflammation
por: Verhagen, Mathijs P., et al.
Publicado: (2023)

Intestinal Intraepithelial Lymphocyte-Enterocyte Crosstalk Regulates Production of Bactericidal Angiogenin 4 by Paneth Cells upon Microbial Challenge
por: Walker, Catherine R., et al.
Publicado: (2013)

Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic Mice
por: Rogala, Allison R., et al.
Publicado: (2020)

Neoplastic Paneth cells in the experimental murine carcinoma of the small intestine.
por: Kim, W. H., et al.
Publicado: (1990)

Plasticity of Paneth cells and their ability to regulate intestinal stem cells
por: Mei, Xianglin, et al.
Publicado: (2020)

Paneth cells as the cornerstones of intestinal and organismal health: a primer
por: Wallaeys, Charlotte, et al.
Publicado: (2022)

Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice
por: Ellermann, Melissa, et al.
Publicado: (2019)

Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
por: Shorning, Boris Y., et al.
Publicado: (2009)

Intestinal GPCRs Control Paneth Cell Maturation and Susceptibility to Experimental Colitis
por: Zhang, Xiao, et al.
Publicado: (2016)

Oral Administration of Probiotics Increases Paneth Cells and Intestinal Antimicrobial Activity
por: Cazorla, Silvia I., et al.
Publicado: (2018)

Two-photon microscopy of Paneth cells in the small intestine of live mice
por: Jang, Won Hyuk, et al.
Publicado: (2018)

Paneth cell–derived growth factors support tumorigenesis in the small intestine
por: Chen, Qing, et al.
Publicado: (2020)

From birth to death: The hardworking life of Paneth cell in the small intestine
por: Cui, Chenbin, et al.
Publicado: (2023)

Multifaceted involvements of Paneth cells in various diseases within intestine and systemically
por: Cui, Chenbin, et al.
Publicado: (2023)

Paneth cells mediated the response of intestinal stem cells at the early stage of intestinal inflammation in the chicken
por: Yu, Lingzi, et al.
Publicado: (2020)

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
por: Shorning, Boris Y., et al.
Publicado: (2009)

Correction: Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine
por: Shorning, Boris Y., et al.
Publicado: (2019)

Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract
por: Karlsson, Jenny, et al.
Publicado: (2008)

A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation
por: Schneider, Marlon R., et al.
Publicado: (2010)

Evidence for a Crucial Role of Paneth Cells in Mediating the Intestinal Response to Injury
por: Parry, Lee, et al.
Publicado: (2013)

In the Wnt of Paneth Cells: Immune-Epithelial Crosstalk in Small Intestinal Crohn’s Disease
por: Armbruster, Nicole S., et al.
Publicado: (2017)

Expression and Localization of Paneth Cells and Their α-Defensins in the Small Intestine of Adult Mouse
por: Nakamura, Kiminori, et al.
Publicado: (2020)

Cdk5rap3 is essential for intestinal Paneth cell development and maintenance
por: Quintero, Michaela, et al.
Publicado: (2021)

Paneth cells and necrotizing enterocolitis
por: Underwood, Mark A.
Publicado: (2012)

Microbial imbalance and intestinal pathologies: connections and contributions
por: Yang, Ye, et al.
Publicado: (2014)

Constitutive STAT5 activation regulates Paneth and Paneth-like cells to control Clostridium difficile colitis
por: Liu, Ruixue, et al.
Publicado: (2019)

Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
por: He, Gui-Wei, et al.
Publicado: (2022)

Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation
por: He, Gui-Wei, et al.
Publicado: (2022)

Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
por: Bastide, Pauline, et al.
Publicado: (2007)

Intestinal commensal microbiota and cytokines regulate Fut2(+) Paneth cells for gut defense
por: Kamioka, Mariko, et al.
Publicado: (2022)

Frizzled 7 modulates goblet and Paneth cell fate, and maintains homeostasis in mouse intestine
por: Gu, Nai-Xin, et al.
Publicado: (2023)

DeMISTifying Paneth Cell Maturation
por: Spatz, Lillian B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9mqika6e3il3ovbd5tkt912e8f