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Regulation of CK2 by Phosphorylation and O-GlcNAcylation Revealed by Semisynthesis

Protein Ser/Thr kinase CK2 (casein kinase II) is involved in a myriad of cellular processes including cell growth and proliferation by phosphorylating hundreds of substrates, yet the regulation process of CK2 function is poorly understood. Here we report that the CK2 catalytic subunit CK2α is modifi...

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Detalles Bibliográficos
Autores principales: Tarrant, Mary Katherine, Rho, Hee-Sool, Xie, Zhi, Jiang, Yu Lin, Gross, Christopher, Culhane, Jeffrey C., Yan, Gai, Qian, Jiang, Ichikawa, Yoshitaka, Matsuoka, Tatsuji, Zachara, Natasha, Etzkorn, Felicia A., Hart, Gerald W., Jeong, Jun Seop, Blackshaw, Seth, Zhu, Heng, Cole, Philip A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288285/
https://www.ncbi.nlm.nih.gov/pubmed/22267120
http://dx.doi.org/10.1038/nchembio.771

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