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CLIPR-59 regulates TNF-α-induced apoptosis by controlling ubiquitination of RIP1
Tumor necrosis factor-α (TNF-α) has important roles in several immunological events by regulating apoptosis and transcriptional activation of cytokine genes. Intracellular signaling mediated by TNF-receptor-type 1 (TNFR1) is constituted by two sequential protein complexes: Complex-I containing the r...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288345/ https://www.ncbi.nlm.nih.gov/pubmed/22297296 http://dx.doi.org/10.1038/cddis.2012.3 |