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Somatic Histone H3 Alterations in Paediatric Diffuse Intrinsic Pontine Gliomas and Non-Brainstem Glioblastomas
To identify somatic mutations in paediatric diffuse intrinsic pontine gliomas (DIPGs), we performed whole genome sequencing of 7 DIPGs and matched germline DNA, and targeted sequencing of an additional 43 DIPGs and 36 non-brainstem paediatric glioblastomas (non-BS-PGs). 78% of DIPGs and 22% of non-B...
Autores principales: | Wu, Gang, Broniscer, Alberto, McEachron, Troy A, Lu, Charles, Paugh, Barbara S, Becksfort, Jared, Qu, Chunxu, Ding, Li, Huether, Robert, Parker, Matthew, Zhang, Junyuan, Gajjar, Amar, Dyer, Michael A, Mullighan, Charles G, Gilbertson, Richard J, Mardis, Elaine R., Wilson, Richard K., Downing, James R, Ellison, David W, Zhang, Jinghui, Baker, Suzanne J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288377/ https://www.ncbi.nlm.nih.gov/pubmed/22286216 http://dx.doi.org/10.1038/ng.1102 |
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