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Bayesian non-negative factor analysis for reconstructing transcription factor mediated regulatory networks

BACKGROUND: Transcriptional regulation by transcription factor (TF) controls the time and abundance of mRNA transcription. Due to the limitation of current proteomics technologies, large scale measurements of protein level activities of TFs is usually infeasible, making computational reconstruction...

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Detalles Bibliográficos
Autores principales: Meng, Jia, Zhang, Jianqiu (Michelle), Chen, Yidong, Huang, Yufei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289087/
https://www.ncbi.nlm.nih.gov/pubmed/22166063
http://dx.doi.org/10.1186/1477-5956-9-S1-S9