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Bayesian non-negative factor analysis for reconstructing transcription factor mediated regulatory networks
BACKGROUND: Transcriptional regulation by transcription factor (TF) controls the time and abundance of mRNA transcription. Due to the limitation of current proteomics technologies, large scale measurements of protein level activities of TFs is usually infeasible, making computational reconstruction...
Autores principales: | Meng, Jia, Zhang, Jianqiu (Michelle), Chen, Yidong, Huang, Yufei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289087/ https://www.ncbi.nlm.nih.gov/pubmed/22166063 http://dx.doi.org/10.1186/1477-5956-9-S1-S9 |
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