In vitro release and in vitro–in vivo correlation for silybin meglumine incorporated into hollow-type mesoporous silica nanoparticles

BACKGROUND: The purpose of this study was to develop a sustained drug-release model for water-soluble drugs using silica nanoparticles. METHODS: Hollow-type mesoporous silica nanoparticles (HMSNs) were prepared using Na(2)CO(3) solution as the dissolution medium for the first time. The water-soluble...

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Detalles Bibliográficos
Autores principales: Cao, Xia, Deng, Wen-Wen, Fu, Min, Wang, Liang, Tong, Shan-Shan, Wei, Ya-Wei, Xu, Ying, Su, Wei-Yan, Xu, Xi-ming, Yu, Jiang-Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289441/
https://www.ncbi.nlm.nih.gov/pubmed/22393284
http://dx.doi.org/10.2147/IJN.S28348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289441/
https://www.ncbi.nlm.nih.gov/pubmed/22393284
http://dx.doi.org/10.2147/IJN.S28348

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