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Development and Characterization of a Reverse Genetic System for Studying Dengue Virus Serotype 3 Strain Variation and Neutralization
Dengue viruses (DENV) are enveloped single-stranded positive-sense RNA viruses transmitted by Aedes spp. mosquitoes. There are four genetically distinct serotypes designated DENV-1 through DENV-4, each further subdivided into distinct genotypes. The dengue scientific community has long contended tha...
Autores principales: | Messer, William B., Yount, Boyd, Hacker, Kari E., Donaldson, Eric F., Huynh, Jeremy P., de Silva, Aravinda M., Baric, Ralph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289595/ https://www.ncbi.nlm.nih.gov/pubmed/22389731 http://dx.doi.org/10.1371/journal.pntd.0001486 |
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