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Dengue Virus Infection-Enhancing Activity in Serum Samples with Neutralizing Activity as Determined by Using FcγR-Expressing Cells

BACKGROUND: Progress in dengue vaccine development has been hampered by limited understanding of protective immunity against dengue virus infection. Conventional neutralizing antibody titration assays that use FcγR-negative cells do not consider possible infection-enhancement activity. We reasoned t...

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Detalles Bibliográficos
Autores principales: Moi, Meng Ling, Lim, Chang-Kweng, Chua, Kaw Bing, Takasaki, Tomohiko, Kurane, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289619/
https://www.ncbi.nlm.nih.gov/pubmed/22389741
http://dx.doi.org/10.1371/journal.pntd.0001536