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Structural Stability of Human Protein Tyrosine Phosphatase ρ Catalytic Domain: Effect of Point Mutations

Protein tyrosine phosphatase ρ (PTPρ) belongs to the classical receptor type IIB family of protein tyrosine phosphatase, the most frequently mutated tyrosine phosphatase in human cancer. There are evidences to suggest that PTPρ may act as a tumor suppressor gene and dysregulation of Tyr phosphorylat...

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Detalles Bibliográficos
Autores principales:	Pasquo, Alessandra, Consalvi, Valerio, Knapp, Stefan, Alfano, Ivan, Ardini, Matteo, Stefanini, Simonetta, Chiaraluce, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289658/ https://www.ncbi.nlm.nih.gov/pubmed/22389709 http://dx.doi.org/10.1371/journal.pone.0032555

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