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The RNA Polymerase PB2 Subunit of Influenza A/HongKong/156/1997 (H5N1) Restrict the Replication of Reassortant Ribonucleoprotein Complexes

BACKGROUND: Genetic reassortment plays a critical role in the generation of pandemic strains of influenza virus. The influenza virus RNA polymerase, composed of PB1, PB2 and PA subunits, has been suggested to influence the efficiency of genetic reassortment. However, the role of the RNA polymerase i...

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Detalles Bibliográficos
Autores principales: Nakazono, Yoko, Hara, Koyu, Kashiwagi, Takahito, Hamada, Nobuyuki, Watanabe, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289661/
https://www.ncbi.nlm.nih.gov/pubmed/22389716
http://dx.doi.org/10.1371/journal.pone.0032634