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THE CD133-POSITIVE COLON CANCER CELL PHENOTYPE IS MORE INTERACTIVE WITH THE TUMOR MICROENVIRONMENT COMPARED TO CD133-NEGATIVE CELL

Experimental data indicate that colorectal cancer cells with CD133 expression exhibit enhanced tumorigenicity over CD133− cells. We hypothesized that CD133+ cells, compared to CD133−, are more tumorigenic because they are more interactive with and responsive to their stromal microenvironment. Freshl...

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Detalles Bibliográficos
Autores principales: Chao, Celia, Carmical, J. Russ, Ives, Kirk, Wood, Thomas G., Aronson, Judith F., Gomez, Guillermo, Djukom, Clarisse D., Hellmich, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289715/
https://www.ncbi.nlm.nih.gov/pubmed/22157717
http://dx.doi.org/10.1038/labinvest.2011.185