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B Cell Responses to CpG Correlate with CXCL16 Expression Levels in Common Variable Immunodeficiency

Broad Toll-like receptor 9 (TLR9) signalling defects after CpG in vitro stimulation have been described in common variable immunodeficiency (CVID). CXCL16, a surface receptor, was recently shown to influence cell responses to CpG. We evaluated the expression and function of CXCL16 on B cells from he...

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Detalles Bibliográficos
Autores principales: Lougaris, Vassilios, Baronio, Manuela, Vitali, Massimiliano, Tampella, Giacomo, Soresina, Annarosa, Badolato, Raffaele, Plebani, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289902/
https://www.ncbi.nlm.nih.gov/pubmed/22454615
http://dx.doi.org/10.1100/2012/960219