Marked Reduction of AKT1 Expression and Deregulation of AKT1-Associated Pathways in Peripheral Blood Mononuclear Cells of Schizophrenia Patients

BACKGROUND: Recent studies have suggested that deregulated AKT1 signaling is associated with schizophrenia. We hypothesized that if this is indeed the case, we should observe both decreased AKT1 expression as well as deregulation of AKT1 regulated pathways in Peripheral Blood Mononuclear Cells (PBMC...

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Detalles Bibliográficos
Autores principales: van Beveren, Nico J. M., Buitendijk, Gabrielle H. S., Swagemakers, Sigrid, Krab, Lianne C., Röder, Christian, de Haan, Lieuwe, van der Spek, Peter, Elgersma, Ype
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290567/
https://www.ncbi.nlm.nih.gov/pubmed/22393424
http://dx.doi.org/10.1371/journal.pone.0032618

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