Tensor-Based Morphometry and Stereology Reveal Brain Pathology in the Complexin1 Knockout Mouse

Complexins (Cplxs) are small, soluble, regulatory proteins that bind reversibly to the SNARE complex and modulate synaptic vesicle release. Cplx1 knockout mice (Cplx1(−/−)) have the earliest known onset of ataxia seen in a mouse model, although hitherto no histopathology has been described in these...

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Detalles Bibliográficos
Autores principales: Kielar, Catherine, Sawiak, Stephen J., Navarro Negredo, Paloma, Tse, Desmond H. Y., Morton, A. Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290572/
https://www.ncbi.nlm.nih.gov/pubmed/22393426
http://dx.doi.org/10.1371/journal.pone.0032636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290572/
https://www.ncbi.nlm.nih.gov/pubmed/22393426
http://dx.doi.org/10.1371/journal.pone.0032636

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