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Tensor-Based Morphometry and Stereology Reveal Brain Pathology in the Complexin1 Knockout Mouse
Complexins (Cplxs) are small, soluble, regulatory proteins that bind reversibly to the SNARE complex and modulate synaptic vesicle release. Cplx1 knockout mice (Cplx1(−/−)) have the earliest known onset of ataxia seen in a mouse model, although hitherto no histopathology has been described in these...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290572/ https://www.ncbi.nlm.nih.gov/pubmed/22393426 http://dx.doi.org/10.1371/journal.pone.0032636 |