Cargando…

Cationic Amino Acid Uptake Constitutes a Metabolic Regulation Mechanism and Occurs in the Flagellar Pocket of Trypanosoma cruzi

Trypanosomatids' amino acid permeases are key proteins in parasite metabolism since they participate in the adaptation of parasites to different environments. Here, we report that TcAAP3, a member of a Trypanosoma cruzi multigene family of permeases, is a bona fide arginine transporter. Most hi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miranda, Mariana R., Sayé, Melisa, Bouvier, León A., Cámara, María de los Milagros, Montserrat, Javier, Pereira, Claudio A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290608/ https://www.ncbi.nlm.nih.gov/pubmed/22393446 http://dx.doi.org/10.1371/journal.pone.0032760

Ejemplares similares

A Novel Trypanosoma cruzi Protein Associated to the Flagellar Pocket of Replicative Stages and Involved in Parasite Growth
por: Durante, Ignacio M., et al.
Publicado: (2015)

Proline Modulates the Trypanosoma cruzi Resistance to Reactive Oxygen Species and Drugs through a Novel D, L-Proline Transporter
por: Sayé, Melisa, et al.
Publicado: (2014)

Flagellar Motility of Trypanosoma cruzi Epimastigotes
por: Ballesteros-Rodea, G., et al.
Publicado: (2012)

Nicastrin-Like, a Novel Transmembrane Protein from Trypanosoma cruzi Associated to the Flagellar Pocket
por: Lechuga, Guilherme Curty, et al.
Publicado: (2021)

Erratum to “Flagellar Motility of Trypanosoma cruzi Epimastigotes”
por: Ballesteros-Rodea, G., et al.
Publicado: (2012)

Molecular and Functional Characterization of a Trypanosoma cruzi Nuclear Adenylate Kinase Isoform
por: Cámara, María de los Milagros, et al.
Publicado: (2013)

Plasmid Vectors and Molecular Building Blocks for the Development of Genetic Manipulation Tools for Trypanosoma cruzi
por: Bouvier, León A., et al.
Publicado: (2013)

Repurposing of terconazole as an anti Trypanosoma cruzi agent
por: Reigada, Chantal, et al.
Publicado: (2019)

Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi
por: Reigada, Chantal, et al.
Publicado: (2017)

Proximity-dependent biotinylation and identification of flagellar proteins in Trypanosoma cruzi
por: Won, Madalyn M., et al.
Publicado: (2023)

Proximity-Dependent Biotinylation and Identification of Flagellar Proteins in Trypanosoma cruzi
por: Won, Madalyn M., et al.
Publicado: (2023)

Structural Changes of the Paraflagellar Rod during Flagellar Beating in Trypanosoma cruzi
por: Rocha, Gustavo Miranda, et al.
Publicado: (2010)

Assembly mechanism of Trypanosoma brucei BILBO1 at the flagellar pocket collar
por: Vidilaseris, Keni, et al.
Publicado: (2015)

Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing
por: Reigada, Chantal, et al.
Publicado: (2019)

Role of Trypanosoma cruzi nucleoside diphosphate kinase 1 in DNA damage responses
por: Reigada, Chantal, et al.
Publicado: (2020)

Molecular and antigenic characterization of Trypanosoma cruzi TolT proteins
por: Lobo, Maite, et al.
Publicado: (2019)

BILBO1 Is a Scaffold Protein of the Flagellar Pocket Collar in the Pathogen Trypanosoma brucei
por: Florimond, Célia, et al.
Publicado: (2015)

ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei
por: Brennand, Ana, et al.
Publicado: (2015)

The Trypomastigote Small Surface Antigen (TSSA) regulates Trypanosoma cruzi infectivity and differentiation
por: Cámara, María de los Milagros, et al.
Publicado: (2017)

Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology
por: Lantos, Andrés B., et al.
Publicado: (2016)

Correction: BILBO1 Is a Scaffold Protein of the Flagellar Pocket Collar in the Pathogen Trypanosoma brucei
por: Florimond, Célia, et al.
Publicado: (2015)

Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar
por: Isch, Charlotte, et al.
Publicado: (2021)

Molecular and Electrophysiological Characterization of a Novel Cation Channel of Trypanosoma cruzi
por: Jimenez, Veronica, et al.
Publicado: (2012)

A Trypanosoma brucei Protein Required for Maintenance of the Flagellum Attachment Zone and Flagellar Pocket ER Domains
por: Lacomble, Sylvain, et al.
Publicado: (2012)

The Trypanosoma cruzi Protein TcHTE Is Critical for Heme Uptake
por: Merli, Marcelo L., et al.
Publicado: (2016)

Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi
por: Quiñones, Wilfredo, et al.
Publicado: (2020)

Trypanosoma cruzi surface mucins are involved in the attachment to the Triatoma infestans rectal ampoule
por: Cámara, María de los Milagros, et al.
Publicado: (2019)

Uptake of l-Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi
por: Girard, Richard M. B. M., et al.
Publicado: (2018)

Iron Uptake Controls Trypanosoma cruzi Metabolic Shift and Cell Proliferation
por: Dick, Claudia F., et al.
Publicado: (2023)

Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei
por: Albisetti, Anna, et al.
Publicado: (2017)

Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069
por: Sayé, Melisa, et al.
Publicado: (2020)

Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes
por: Acosta, Héctor, et al.
Publicado: (2019)

Integrative approaches to investigate the structure and assembly of Trypanosoma brucei BILBO1, a multidomain cytoskeletal protein at the flagellar pocket collar
por: Vidilaseris, K, et al.
Publicado: (2015)

Bhalin, an Essential Cytoskeleton-Associated Protein of Trypanosoma brucei Linking TbBILBO1 of the Flagellar Pocket Collar with the Hook Complex
por: Broster Reix, Christine E., et al.
Publicado: (2021)

CRISPR/Cas9-Induced Disruption of Paraflagellar Rod Protein 1 and 2 Genes in Trypanosoma cruzi Reveals Their Role in Flagellar Attachment
por: Lander, Noelia, et al.
Publicado: (2015)

Trypanosoma cruzi-infected triatomines and rodents co-occur in a coastal island of northern Chile
por: Campos-Soto, Ricardo, et al.
Publicado: (2020)

Profiling the Trypanosoma cruzi Phosphoproteome
por: Marchini, Fabricio K., et al.
Publicado: (2011)

Clathrin expression in Trypanosoma cruzi
por: Kalb, Ligia Cristina, et al.
Publicado: (2014)

Endothelial Transmigration by Trypanosoma cruzi
por: Coates, Bria M., et al.
Publicado: (2013)

The N-myristoylome of Trypanosoma cruzi
por: Roberts, Adam J., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ph66tdcan0kpvnivbui356l5f9