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Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer's Disease

BACKGROUND: The identification of early mechanisms underlying Alzheimer's Disease (AD) and associated biomarkers could advance development of new therapies and improve monitoring and predicting of AD progression. Mitochondrial dysfunction has been suggested to underlie AD pathophysiology, howev...

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Detalles Bibliográficos
Autores principales:	Trushina, Eugenia, Nemutlu, Emirhan, Zhang, Song, Christensen, Trace, Camp, Jon, Mesa, Janny, Siddiqui, Ammar, Tamura, Yasushi, Sesaki, Hiromi, Wengenack, Thomas M., Dzeja, Petras P., Poduslo, Joseph F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290628/ https://www.ncbi.nlm.nih.gov/pubmed/22393443 http://dx.doi.org/10.1371/journal.pone.0032737

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