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IRE1 directs proteasomal and lysosomal degradation of misfolded rhodopsin

Endoplasmic reticulum (ER) is responsible for folding of secreted and membrane proteins in eukaryotic cells. Disruption of ER protein folding leads to ER stress. Chronic ER stress can cause cell death and is proposed to underlie the pathogenesis of many human diseases. Inositol-requiring enzyme 1 (I...

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Detalles Bibliográficos
Autores principales:	Chiang, Wei-Chieh, Messah, Carissa, Lin, Jonathan H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290636/ https://www.ncbi.nlm.nih.gov/pubmed/22219383 http://dx.doi.org/10.1091/mbc.E11-08-0663

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