Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets

Apolipoprotein B-100 (ApoB) is the principal component of very low density lipoprotein. Poorly lipidated nascent ApoB is extracted from the Sec61 translocon and degraded by proteasomes. ApoB lipidated in the endoplasmic reticulum (ER) lumen is also subjected to proteasomal degradation, but where and...

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Detalles Bibliográficos
Autores principales: Suzuki, Michitaka, Otsuka, Toshihiko, Ohsaki, Yuki, Cheng, Jinglei, Taniguchi, Takako, Hashimoto, Hisashi, Taniguchi, Hisaaki, Fujimoto, Toyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290640/
https://www.ncbi.nlm.nih.gov/pubmed/22238364
http://dx.doi.org/10.1091/mbc.E11-11-0950

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