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Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY

Junction-mediating and regulatory protein (JMY) is a regulator of both transcription and actin filament assembly. In response to DNA damage, JMY accumulates in the nucleus and promotes p53-dependent apoptosis. JMY's actin-regulatory activity relies on a cluster of three actin-binding Wiskott–Al...

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Detalles Bibliográficos
Autores principales:	Zuchero, J. Bradley, Belin, Brittany, Mullins, R. Dyche
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290644/ https://www.ncbi.nlm.nih.gov/pubmed/22262458 http://dx.doi.org/10.1091/mbc.E11-12-0992

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