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Caveolin targeting to late endosome/lysosomal membranes is induced by perturbations of lysosomal pH and cholesterol content

Caveolin-1 is an integral membrane protein of plasma membrane caveolae. Here we report that caveolin-1 collects at the cytosolic surface of lysosomal membranes when cells are serum starved. This is due to an elevation of the intralysosomal pH, since ionophores and proton pump inhibitors that dissipa...

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Detalles Bibliográficos
Autores principales:	Mundy, Dorothy I., Li, Wei Ping, Luby-Phelps, Katherine, Anderson, Richard G. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290645/ https://www.ncbi.nlm.nih.gov/pubmed/22238363 http://dx.doi.org/10.1091/mbc.E11-07-0598

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