A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA damage response

Repair of DNA double strand breaks is critical to genomic stability and the prevention of developmental disorders and cancer. A central pathway for this repair is homologous recombination (HR). Most knowledge of HR is derived from work in prokaryotic and eukaryotic model organisms. We performed a ge...

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Detalles Bibliográficos
Autores principales: Adamson, Britt, Smogorzewska, Agata, Sigoillot, Frederic D., King, Randall W., Elledge, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290715/
https://www.ncbi.nlm.nih.gov/pubmed/22344029
http://dx.doi.org/10.1038/ncb2426

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