Cargando…
Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression
The Polycomb transcription repressor BMI1 is highly expressed in human neuroblastomas and is required for the clonogenic self-renewal and tumorigenicity of human neuroblastoma cell lines. The molecular basis of BMI1 action in neuroblastoma cells is not well understood. Here we report that BMI1 has a...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290747/ https://www.ncbi.nlm.nih.gov/pubmed/22120721 http://dx.doi.org/10.1038/onc.2011.536 |