Cargando…

aV integrins and TGF-β-induced EMT: a circle of regulation

Transforming growth factor-β (TGF-β) has roles in embryonic development, the prevention of inappropriate inflammation and tumour suppression. However, TGF-β signalling also regulates pathological epithelial-to-mesenchymal transition (EMT), inducing or progressing a number of diseases ranging from in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mamuya, Fahmy A, Duncan, Melinda K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290750/ https://www.ncbi.nlm.nih.gov/pubmed/21883891 http://dx.doi.org/10.1111/j.1582-4934.2011.01419.x

Ejemplares similares

The roles of α(V) integrins in lens EMT and posterior capsular opacification
por: Mamuya, Fahmy A, et al.
Publicado: (2014)

αvβ3 Integrin induces partial EMT independent of TGF-β signaling
por: Kariya, Yoshinobu, et al.
Publicado: (2021)

Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer
por: Andreucci, Elena, et al.
Publicado: (2023)

TGF-β in developmental and fibrogenic EMTs
por: Lee, Jun Ho, et al.
Publicado: (2022)

Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin–ɑvβ6 integrin in liver fibrosis
por: Xu, Ting, et al.
Publicado: (2020)

Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells
por: Mori, Seiji, et al.
Publicado: (2015)

TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer
por: Kim, Bit Na, et al.
Publicado: (2020)

Angiotensin Inhibition, TGF-β and EMT in Cancer
por: Pallasch, Fabian Bernhard, et al.
Publicado: (2020)

Integrin-linked kinase tunes cell–cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1
por: Kilinc, Ayse Nihan, et al.
Publicado: (2021)

FOXM1 Regulated by ERK Pathway MediatesTGF-β1-Induced EMT in NSCLC
por: Kong, Fei-Fei, et al.
Publicado: (2014)

Regulation of TGF-β1-Induced EMT by Autophagy-Dependent Energy Metabolism in Cancer Cells
por: Hwang, Jin Seok, et al.
Publicado: (2022)

TGFβ(1 )signaling via α(V)β(6 )integrin
por: Kracklauer, Martin P, et al.
Publicado: (2003)

Retraction: TGFβ(1 )signaling via a(V)β(6 )integrin
por: Kracklauer, Martin P, et al.
Publicado: (2004)

BMP-2 Induces Versican and Hyaluronan That Contribute to Post-EMT AV Cushion Cell Migration
por: Inai, Kei, et al.
Publicado: (2013)

Establishment of a TGFβ-Induced Post-Transcriptional EMT Gene Signature
por: Hussey, George S., et al.
Publicado: (2012)

ICAM1 promotes bone metastasis via integrin‐mediated TGF‐β/EMT signaling in triple‐negative breast cancer
por: Chen, Mingcang, et al.
Publicado: (2022)

LncRNA ANCR down-regulation promotes TGF-β-induced EMT and metastasis in breast cancer
por: Li, Zhongwei, et al.
Publicado: (2017)

FGF-2 Differentially Regulates Lens Epithelial Cell Behaviour during TGF-β-Induced EMT
por: Flokis, Mary, et al.
Publicado: (2023)

Inhibition of Integrin αvβ6 Activation of TGF‐β Attenuates Tendinopathy
por: Wang, Xiao, et al.
Publicado: (2022)

A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8
por: Le, Viet Q., et al.
Publicado: (2023)

TGF-β isoforms induce EMT independent migration of ovarian cancer cells
por: Gao, Jingfang, et al.
Publicado: (2014)

Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks
por: Zhang, Jingyu, et al.
Publicado: (2016)

PTBP3 mediates TGF-β-induced EMT and metastasis of lung adenocarcinoma
por: Dong, Chenglai, et al.
Publicado: (2022)

Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT
por: Rabie, Emann M., et al.
Publicado: (2021)

TGFβ Drives Metabolic Perturbations during Epithelial Mesenchymal Transition in Pancreatic Cancer: TGFβ Induced EMT in PDAC
por: Rajagopal, Meena U., et al.
Publicado: (2021)

Berberine Suppresses EMT in Liver and Gastric Carcinoma Cells through Combination with TGFβR Regulating TGF-β/Smad Pathway
por: Du, Haiyan, et al.
Publicado: (2021)

Integrin α(V)β(6)-mediated activation of latent TGF-β requires the latent TGF-β binding protein-1
por: Annes, Justin P., et al.
Publicado: (2004)

TGFβ-mediated expression of TGFβ-activating integrins in SSc monocytes: disturbed activation of latent TGFβ?
por: van Caam, A., et al.
Publicado: (2020)

IGHG1 induces EMT in gastric cancer cells by regulating TGF-β/SMAD3 signaling pathway
por: Li, Yuxuan, et al.
Publicado: (2021)

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β
por: Parvani, Jenny G., et al.
Publicado: (2013)

TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
por: Kasai, Hidenori, et al.
Publicado: (2005)

TGF-β2-induced EMT is dampened by inhibition of autophagy and TNF-α treatment
por: Dash, Subhra, et al.
Publicado: (2018)

TGF-β-induced alternative splicing of TAK1 promotes EMT and drug resistance
por: Tripathi, Veenu, et al.
Publicado: (2019)

Changes in mitochondrial function during EMT induced by TGFβ-1 in pancreatic cancer
por: Guo, Qingqu
Publicado: (2017)

LncRNA MALAT1 Modulates TGF-β1-Induced EMT in Keratinocyte
por: Zhang, Liping, et al.
Publicado: (2021)

Quaking 5 suppresses TGF‐β‐induced EMT and cell invasion in lung adenocarcinoma
por: Wang, Shengjie, et al.
Publicado: (2021)

Regulation of TGFβ in the immune system: An emerging role for integrins and dendritic cells
por: Worthington, John J., et al.
Publicado: (2012)

Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway
por: Rapisarda, Valentina, et al.
Publicado: (2017)

Human monocytes and macrophages regulate immune tolerance via integrin αvβ8–mediated TGFβ activation
por: Kelly, Aoife, et al.
Publicado: (2018)

The role of integrins in TGFβ activation in the tumour stroma
por: Khan, Zareen, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_2ssvamh8op3nl7k1ka1tmb4247