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Compensatory Thrombopoietin Production from the Liver and Bone Marrow Stimulates Thrombopoiesis of Living Rat Megakaryocytes in Chronic Renal Failure

BACKGROUND/AIMS: Decreased thrombopoiesis has been ascribed a role in the pathogenesis of uremic bleeding in chronic renal failure (CRF). However, serum thrombopoietin (TPO) levels are usually elevated in CRF patients, suggesting increased thrombopoiesis. The aim of this study was to determine the t...

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Detalles Bibliográficos
Autores principales:	Kazama, Itsuro, Endo, Yasuhiro, Toyama, Hiroaki, Ejima, Yutaka, Kurosawa, Shin, Murata, Yoshimichi, Matsubara, Mitsunobu, Maruyama, Yoshio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2011
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290854/ https://www.ncbi.nlm.nih.gov/pubmed/22470388 http://dx.doi.org/10.1159/000333018

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