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Signaling Mechanisms in the Regulation of Renal Matrix Metabolism in Diabetes

Renal hypertrophy and accumulation of extracellular matrix proteins are among cardinal manifestations of diabetic nephropathy. TGF beta system has been implicated in the pathogenesis of these manifestations. Among signaling pathways activated in the kidney in diabetes, mTOR- (mammalian target of rap...

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Detalles Bibliográficos
Autor principal: Mariappan, Meenalakshmi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290898/
https://www.ncbi.nlm.nih.gov/pubmed/22454628
http://dx.doi.org/10.1155/2012/749812