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Signaling Mechanisms in the Regulation of Renal Matrix Metabolism in Diabetes
Renal hypertrophy and accumulation of extracellular matrix proteins are among cardinal manifestations of diabetic nephropathy. TGF beta system has been implicated in the pathogenesis of these manifestations. Among signaling pathways activated in the kidney in diabetes, mTOR- (mammalian target of rap...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290898/ https://www.ncbi.nlm.nih.gov/pubmed/22454628 http://dx.doi.org/10.1155/2012/749812 |