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Effects of Brugmansia arborea Extract and Its Secondary Metabolites on Morphine Tolerance and Dependence in Mice

The aim of the present study was to investigate, in vivo, the effect of a Brugmansia arborea extract (BRU), chromatographic fractions (FA and FNA), and isolated alkaloids on the expression and the acquisition of morphine tolerance and dependence. Substances were acutely (for expression) or repeatedl...

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Detalles Bibliográficos
Autores principales:	Mattioli, Laura, Bracci, Antonio, Titomanlio, Federica, Perfumi, Marina, De Feo, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290905/ https://www.ncbi.nlm.nih.gov/pubmed/22454681 http://dx.doi.org/10.1155/2012/741925

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