Cargando…

Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia

Hesperetin, a selective phosphodiesterase (PDE)4 inhibitor, is present in the traditional Chinese medicine, “Chen Pi.” Therefore, we were interested in investigating its effects on ovalbumin- (OVA-) induced airway hyperresponsiveness, and clarifying its rationale for ameliorating asthma and chronic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shih, Chung-Hung, Lin, Ling-Hung, Hsu, Hsin-Te, Wang, Kuo-Hsien, Lai, Chi-Yin, Chen, Chien-Ming, Ko, Wun-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290907/ https://www.ncbi.nlm.nih.gov/pubmed/22454667 http://dx.doi.org/10.1155/2012/472897

Ejemplares similares

Hesperetin-5,7,3’-O-triacetate suppresses airway hyperresponsiveness in ovalbumin-sensitized and challenged mice without reversing xylazine/ketamine-induced anesthesia in normal mice
por: Yang, You-Lan, et al.
Publicado: (2017)

Hesperetin-7,3'-O-dimethylether selectively inhibits phosphodiesterase 4 and effectively suppresses ovalbumin-induced airway hyperresponsiveness with a high therapeutic ratio
por: Yang, You-Lan, et al.
Publicado: (2011)

Biochanin A, a Phytoestrogenic Isoflavone with Selective Inhibition of Phosphodiesterase 4, Suppresses Ovalbumin-Induced Airway Hyperresponsiveness
por: Ko, Wun-Chang, et al.
Publicado: (2011)

S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness
por: Shih, Chung-Hung, et al.
Publicado: (2011)

Hesperidin-3′-O-Methylether Is More Potent than Hesperidin in Phosphodiesterase Inhibition and Suppression of Ovalbumin-Induced Airway Hyperresponsiveness
por: Yang, You-Lan, et al.
Publicado: (2012)

Hesperetin-5,7,3ʹ-O-Trimethylether Dually Inhibits Phosphodiesterase 3/4 and Methacholine-Induced Airway Hyperresponsiveness in Sensitized and Challenged Mice
por: Shih, Chung-Hung, et al.
Publicado: (2020)

Effects of Combined Ketamine/Xylazine Anesthesia on Light Induced Retinal Degeneration in Rats
por: Arango-Gonzalez, Blanca, et al.
Publicado: (2012)

Ketamine/Xylazine-Induced Corneal Damage in Mice
por: Koehn, Demelza, et al.
Publicado: (2015)

Correction: Effects of Combined Ketamine/Xylazine Anesthesia on Light Induced Retinal Degeneration in Rats
por: Arango-Gonzalez, Blanca, et al.
Publicado: (2012)

Tanshinone IIA attenuates ovalbumin-induced airway inflammation and hyperresponsiveness in a murine model of asthma
por: Wang, Shi-Biao, et al.
Publicado: (2019)

Correction: Ketamine/Xylazine-Induced Corneal Damage in Mice
Publicado: (2015)

Respiratory Syncytial Virus Reverses Airway Hyperresponsiveness to Methacholine in Ovalbumin-Sensitized Mice
por: Aeffner, Famke, et al.
Publicado: (2012)

The administration of clopidogrel attenuates airway hyperresponsiveness and airway inflammation in an ovalbumin specific allergic asthma model
por: Trinh, Hoang Kim Tu, et al.
Publicado: (2015)

Guaiphenesin-ketamine-xylazine infusion to maintain anesthesia in mules undergoing field castration
por: Vullo, Cecilia, et al.
Publicado: (2017)

Faster emergence behavior from ketamine/xylazine anesthesia with atipamezole versus yohimbine
por: Mees, Lukas, et al.
Publicado: (2018)

Reduced airway hyperresponsiveness by phosphodiesterase 3 and 4 inhibitors in guinea-pigs.
por: Germain, N, et al.
Publicado: (1999)

Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma
por: Mac Sharry, John, et al.
Publicado: (2014)

Castration of Dogs Using Local Anesthesia After Sedating With Xylazine and Subanesthetic Doses of Ketamine
por: Silva, Erika, et al.
Publicado: (2020)

The effects of repeated doses of xylazine-ketamine and medetomidineketamine anesthesia on DNA damage in the liver and kidney
por: Sancak, Tunahan
Publicado: (2023)

Effects of xylazine-ketamine anesthesia on plasma levels of cortisol and vital signs during laparotomy in dogs
por: Naddaf, H., et al.
Publicado: (2014)

Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia
por: Dodelet-Devillers, Aurore, et al.
Publicado: (2016)

Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine
por: Schuetze, Sandra, et al.
Publicado: (2019)

A Smartphone App for Individual Xylazine/Ketamine Calculation Decreased Anesthesia-Related Mortality in Mice
por: Jara, Carlos Poblete, et al.
Publicado: (2021)

Comparison of ketamine/xylazine and isoflurane anesthesia on the establishment of mouse middle cerebral artery occlusion model
por: Gu, Chenyang, et al.
Publicado: (2022)

Effects of nebulized ketamine on allergen-induced airway hyperresponsiveness and inflammation in actively sensitized Brown-Norway rats
por: Zhu, Min Min, et al.
Publicado: (2007)

Intraperitoneal co-administration of low dose urethane with xylazine and ketamine for extended duration of surgical anesthesia in rats
por: Kumar, Arun H. S., et al.
Publicado: (2015)

Impact of repeated anesthesia with ketamine and xylazine on the well-being of C57BL/6JRj mice
por: Hohlbaum, Katharina, et al.
Publicado: (2018)

Comparison of cardiorespiratory and anesthetic effects of ketamine-midazolam-xylazine-sufentanil and tiletamine-zolazepam-xylazine in miniature pigs
por: Zhang, Zhiheng, et al.
Publicado: (2022)

Anesthetic efficacy of ketamine–diazepam, ketamine–xylazine, and ketamine–acepromazine in Caspian Pond turtles (Mauremys caspica)
por: Adel, Milad, et al.
Publicado: (2017)

Interaction Between Daidzein and Hesperetin on Antispasmodic Action in Isolated Sensitized and Non-sensitized Guinea-Pig Tracheas
por: Shih, Chung-Hung, et al.
Publicado: (2016)

Network and synaptic mechanisms underlying high frequency oscillations in the rat and cat olfactory bulb under ketamine-xylazine anesthesia
por: Średniawa, Władysław, et al.
Publicado: (2021)

Classical heart rate variability and nonlinear heart rate analysis in mice under Na-pentobarbital and ketamine/xylazine anesthesia
por: KAZDAĞLI, Hasan, et al.
Publicado: (2022)

Particulate Matter–Induced Airway Hyperresponsiveness Is Lymphocyte Dependent
por: Saunders, Vanessa, et al.
Publicado: (2010)

High fat diet induces airway hyperresponsiveness in mice
por: Fricke, Kathrin, et al.
Publicado: (2018)

Mechanism of Lower Airway Hyperresponsiveness Induced by Allergic Rhinitis
por: Liu, Yiting, et al.
Publicado: (2022)

Effect of the ketamine/xylazine anesthetic on the auditory brainstem response of adult gerbils
por: Lima, J.P., et al.
Publicado: (2012)

Biochemical Effects of Xylazine, Propofol, and Ketamine in West African Dwarf Goats
por: Celestine Okwudili, Ukwueze, et al.
Publicado: (2014)

Exposure to Polyhexamethylene Guanidine Exacerbates Bronchial Hyperresponsiveness and Lung Inflammation in a Mouse Model of Ovalbumin-Induced Asthma
por: Lee, Seung-Hwa, et al.
Publicado: (2021)

Oral Administration of Heat-Inactivated Lactobacillus plantarum K37 Modulated Airway Hyperresponsiveness in Ovalbumin-Sensitized BALB/c Mice
por: Liu, Yen-Wenn, et al.
Publicado: (2014)

Obesity Induced by Neonatal Overfeeding Worsens Airway Hyperresponsiveness and Inflammation
por: Ye, Zehui, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_js7rpal1f8npiv8ta93p5obocd