Cargando…

Zerumbone, a Southeast Asian Ginger Sesquiterpene, Induced Apoptosis of Pancreatic Carcinoma Cells through p53 Signaling Pathway

Pancreatic carcinoma is one common cancer with gradually increasing incidence during the past several decades. However, currently the candidate drugs to suppress pancreatic cancer remain lacking. This research was carried out to investigate if zerumbone, a natural cyclic sesquiterpene isolated from...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Songyan, Liu, Qiaojing, Liu, Yanju, Qiao, Hong, Liu, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290912/ https://www.ncbi.nlm.nih.gov/pubmed/22454691 http://dx.doi.org/10.1155/2012/936030

Ejemplares similares

Zerumbone, Sesquiterpene Photochemical from Ginger, Inhibits Angiogenesis
por: Park, Ju-Hyung, et al.
Publicado: (2015)

Zerumbone, a tropical ginger sesquiterpene, ameliorates streptozotocin-induced diabetic nephropathy in rats by reducing the hyperglycemia-induced inflammatory response
por: Tzeng, Thing-Fong, et al.
Publicado: (2013)

Zerumbone, a Tropical Ginger Sesquiterpene of Zingiber officinale Roscoe, Attenuates α-MSH-Induced Melanogenesis in B16F10 Cells
por: Oh, Taek-In, et al.
Publicado: (2018)

A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extraction from Ginger Rhizomes
por: Kalantari, Katayoon, et al.
Publicado: (2017)

Zerumbone, a Phytochemical of Subtropical Ginger, Protects against Hyperglycemia-Induced Retinal Damage in Experimental Diabetic Rats
por: Tzeng, Thing-Fong, et al.
Publicado: (2016)

Zerumbone, a Bioactive Sesquiterpene, Ameliorates Diabetes-Induced Retinal Microvascular Damage through Inhibition of Phospho-p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways
por: Liu, Wayne Young, et al.
Publicado: (2016)

Zerumbone, a cyclic sesquiterpene, exerts antimitotic activity in HeLa cells through tubulin binding and exhibits synergistic activity with vinblastine and paclitaxel
por: Ashraf, Shabeeba M., et al.
Publicado: (2018)

Effects of zerumbone on proliferation and apoptosis of esophageal cancer cells and on P53 and Bcl-2 expression levels
por: Ma, Shiyang, et al.
Publicado: (2018)

Zerumbone, a Natural Cyclic Sesquiterpene of Zingiber zerumbet Smith, Attenuates Nonalcoholic Fatty Liver Disease in Hamsters Fed on High-Fat Diet
por: Tzeng, Thing-Fong, et al.
Publicado: (2013)

In Vitro Ultramorphological Assessment of Apoptosis Induced by Zerumbone on (HeLa)
por: Abdel Wahab, Siddig Ibrahim, et al.
Publicado: (2009)

Zerumbone Attenuates the Severity of Acute Necrotizing Pancreatitis and Pancreatitis-Induced Hepatic Injury
por: Wenhong, Deng, et al.
Publicado: (2012)

Terpenoids from Zingiber officinale (Ginger) Induce Apoptosis in Endometrial Cancer Cells through the Activation of p53
por: Liu, Yang, et al.
Publicado: (2012)

Antidermatophytic and Protease-inhibiting Activities of Zerumbone: A Natural Sesquiterpene from the Rhizome of Zingiber zerumbet (L.) Roscoe ex J.E; Smith
por: Jyothilakshmi, Madhavankutty, et al.
Publicado: (2017)

Potential of Zerumbone as an Anti-Cancer Agent
por: Girisa, Sosmitha, et al.
Publicado: (2019)

Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells
por: Foong, Jia Ning, et al.
Publicado: (2018)

Zerumbone mediates apoptosis and induces secretion of proinflammatory cytokines in breast carcinoma cell culture
por: Barathan, Muttiah, et al.
Publicado: (2021)

Cysteine-Conjugated Metabolites of Ginger Components, Shogaols, Induce Apoptosis through Oxidative Stress-Mediated p53 Pathway in Human Colon Cancer Cells
por: Fu, Junsheng, et al.
Publicado: (2014)

Zerumbone ameliorates the inflammatory response and organ damage in severe acute pancreatitis via the ROS/NF-κB pathway
por: Zhang, Fengmei, et al.
Publicado: (2023)

Zerumbone Inhibits Helicobacter pylori Urease Activity
por: Woo, Hyun Jun, et al.
Publicado: (2021)

Anticancer bioactivity of zerumbone on pediatric rhabdomyosarcoma cells
por: Urla, Cristian, et al.
Publicado: (2022)

Zerumbone induced apoptosis in liver cancer cells via modulation of Bax/Bcl-2 ratio
por: Sharifah Sakinah, SA, et al.
Publicado: (2007)

Binding Mode Analysis of Zerumbone to Key Signal Proteins in the Tumor Necrosis Factor Pathway
por: Fatima, Ayesha, et al.
Publicado: (2015)

Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells
por: Weng, Hsing-Yu, et al.
Publicado: (2012)

Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis
por: Sobhan, Praveen K., et al.
Publicado: (2013)

A Trip through Southeast Asian Airports in Times of COVID-19
por: Vock, Lorenz
Publicado: (2020)

Correction: Calpain and Reactive Oxygen Species Targets Bax for Mitochondrial Permeabilisation and Caspase Activation in Zerumbone Induced Apoptosis
por: Sobhan, Praveen K., et al.
Publicado: (2022)

Larsenianthus, a new Asian genus of Gingers (Zingiberaceae) with four species
por: Kress, W. John, et al.
Publicado: (2010)

The evolving structure of the Southeast Asian air transport network through the lens of complex networks, 1979–2012
por: Dai, Liang, et al.
Publicado: (2018)

The therapeutic effect of zerumbone on chronic gastritis via antioxidant mechanisms
por: Li, Liqing, et al.
Publicado: (2017)

Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone
por: Hwang, Jayeong, et al.
Publicado: (2020)

Formulation and Nanotechnology-Based Approaches for Solubility and Bioavailability Enhancement of Zerumbone
por: Kesharwani, Siddharth S., et al.
Publicado: (2020)

The Potential Anti-Inflammatory Effects of Zerumbone in COVID-19 Patients
por: Dehghan, Razieh, et al.
Publicado: (2021)

Zerumbone Exhibit Protective Effect against Zearalenone Induced Toxicity via Ameliorating Inflammation and Oxidative Stress Induced Apoptosis
por: AbuZahra, Hamad Mohammed, et al.
Publicado: (2021)

Zerumbone Promotes Cytotoxicity in Human Malignant Glioblastoma Cells through Reactive Oxygen Species (ROS) Generation
por: Jalili-Nik, Mohammad, et al.
Publicado: (2020)

First Southeast Asian Graph Theory Colloquium
por: Koh, Khee, et al.
Publicado: (1984)

Indian genetic heritage in Southeast Asian populations
por: Changmai, Piya, et al.
Publicado: (2022)

Rituximab Therapy for Treatment of Pemphigus in Southeast Asians
por: Kanokrungsee, Silada, et al.
Publicado: (2021)

Dengue in Pregnancy: A Southeast Asian Perspective
por: Chong, Vanessa, et al.
Publicado: (2023)

Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway
por: Zheng, Chunning, et al.
Publicado: (2012)

Dietary zerumbone prevents against ultraviolet B-induced cataractogenesis in the mouse
por: Chen, Bo-Yie, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_08afjkk94h9vurb76d45r24jnl