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Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005
To understand transmission of avian influenza A (H5N1) virus, we conducted a retrospective survey of poultry deaths and a seroepidemiologic investigation in a Cambodian village where a 28-year-old man was infected with H5N1 virus in March 2005. Poultry surveys were conducted within a 1-km radius of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290951/ https://www.ncbi.nlm.nih.gov/pubmed/17176569 http://dx.doi.org/10.3201/eid1210.060424 |
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author | Vong, Sirenda Coghlan, Benjamin Mardy, Sek Holl, Davun Seng, Heng Ly, Sovann Miller, Megge J. Buchy, Philippe Froehlich, Yves Dufourcq, Jean Baptiste Uyeki, Timothy M. Lim, Wilina Sok, Touch |
author_facet | Vong, Sirenda Coghlan, Benjamin Mardy, Sek Holl, Davun Seng, Heng Ly, Sovann Miller, Megge J. Buchy, Philippe Froehlich, Yves Dufourcq, Jean Baptiste Uyeki, Timothy M. Lim, Wilina Sok, Touch |
author_sort | Vong, Sirenda |
collection | PubMed |
description | To understand transmission of avian influenza A (H5N1) virus, we conducted a retrospective survey of poultry deaths and a seroepidemiologic investigation in a Cambodian village where a 28-year-old man was infected with H5N1 virus in March 2005. Poultry surveys were conducted within a 1-km radius of the patient's household. Forty-two household flocks were considered likely to have been infected from January through March 2005 because >60% of the flock died, case-fatality ratio was 100%, and both young and mature birds died within 1 to 2 days. Two sick chickens from a property adjacent to the patient's house tested positive for H5N1 on reverse transcription–PCR. Villagers were asked about poultry exposures in the past year and tested for H5N1 antibodies. Despite frequent, direct contact with poultry suspected of having H5N1 virus infection, none of 351 participants from 93 households had neutralizing antibodies to H5N1. H5N1 virus transmission from poultry to humans remains low in this setting. |
format | Online Article Text |
id | pubmed-3290951 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-32909512012-03-06 Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 Vong, Sirenda Coghlan, Benjamin Mardy, Sek Holl, Davun Seng, Heng Ly, Sovann Miller, Megge J. Buchy, Philippe Froehlich, Yves Dufourcq, Jean Baptiste Uyeki, Timothy M. Lim, Wilina Sok, Touch Emerg Infect Dis Research To understand transmission of avian influenza A (H5N1) virus, we conducted a retrospective survey of poultry deaths and a seroepidemiologic investigation in a Cambodian village where a 28-year-old man was infected with H5N1 virus in March 2005. Poultry surveys were conducted within a 1-km radius of the patient's household. Forty-two household flocks were considered likely to have been infected from January through March 2005 because >60% of the flock died, case-fatality ratio was 100%, and both young and mature birds died within 1 to 2 days. Two sick chickens from a property adjacent to the patient's house tested positive for H5N1 on reverse transcription–PCR. Villagers were asked about poultry exposures in the past year and tested for H5N1 antibodies. Despite frequent, direct contact with poultry suspected of having H5N1 virus infection, none of 351 participants from 93 households had neutralizing antibodies to H5N1. H5N1 virus transmission from poultry to humans remains low in this setting. Centers for Disease Control and Prevention 2006-10 /pmc/articles/PMC3290951/ /pubmed/17176569 http://dx.doi.org/10.3201/eid1210.060424 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Vong, Sirenda Coghlan, Benjamin Mardy, Sek Holl, Davun Seng, Heng Ly, Sovann Miller, Megge J. Buchy, Philippe Froehlich, Yves Dufourcq, Jean Baptiste Uyeki, Timothy M. Lim, Wilina Sok, Touch Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 |
title | Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 |
title_full | Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 |
title_fullStr | Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 |
title_full_unstemmed | Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 |
title_short | Low Frequency of Poultry-to-Human H5N1 Transmission, Southern Cambodia, 2005 |
title_sort | low frequency of poultry-to-human h5n1 transmission, southern cambodia, 2005 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290951/ https://www.ncbi.nlm.nih.gov/pubmed/17176569 http://dx.doi.org/10.3201/eid1210.060424 |
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