Transmission of New Bovine Prion to Mice

We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res)). We show that intracerebral injection of such isolates into C57BL/6...

Descripción completa

Detalles Bibliográficos
Autores principales: Baron, Thierry G.M., Biacabe, Anne-Gaëlle, Bencsik, Anna, Langeveld, Jan P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2006
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291063/
https://www.ncbi.nlm.nih.gov/pubmed/16836832
http://dx.doi.org/10.3201/eid1207.060107
_version_ 1782225086955126784
author Baron, Thierry G.M.
Biacabe, Anne-Gaëlle
Bencsik, Anna
Langeveld, Jan P.M.
author_facet Baron, Thierry G.M.
Biacabe, Anne-Gaëlle
Bencsik, Anna
Langeveld, Jan P.M.
author_sort Baron, Thierry G.M.
collection PubMed
description We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res)). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrP(res) molecular features distinct from BSE.
format Online
Article
Text
id pubmed-3291063
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-32910632012-03-05 Transmission of New Bovine Prion to Mice Baron, Thierry G.M. Biacabe, Anne-Gaëlle Bencsik, Anna Langeveld, Jan P.M. Emerg Infect Dis Dispatch We previously reported that cattle were affected by a prion disorder that differed from bovine spongiform encephalopathy (BSE) by showing distinct molecular features of disease-associated protease-resistant prion protein (PrP(res)). We show that intracerebral injection of such isolates into C57BL/6 mice produces a disease with preservation of PrP(res) molecular features distinct from BSE. Centers for Disease Control and Prevention 2006-07 /pmc/articles/PMC3291063/ /pubmed/16836832 http://dx.doi.org/10.3201/eid1207.060107 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Baron, Thierry G.M.
Biacabe, Anne-Gaëlle
Bencsik, Anna
Langeveld, Jan P.M.
Transmission of New Bovine Prion to Mice
title Transmission of New Bovine Prion to Mice
title_full Transmission of New Bovine Prion to Mice
title_fullStr Transmission of New Bovine Prion to Mice
title_full_unstemmed Transmission of New Bovine Prion to Mice
title_short Transmission of New Bovine Prion to Mice
title_sort transmission of new bovine prion to mice
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291063/
https://www.ncbi.nlm.nih.gov/pubmed/16836832
http://dx.doi.org/10.3201/eid1207.060107
work_keys_str_mv AT baronthierrygm transmissionofnewbovinepriontomice
AT biacabeannegaelle transmissionofnewbovinepriontomice
AT bencsikanna transmissionofnewbovinepriontomice
AT langeveldjanpm transmissionofnewbovinepriontomice

Ejemplares similares