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VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France

VEB-1 extended-spectrum β-lactamase–producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and labor...

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Autores principales: Naas, Thierry, Coignard, Bruno, Carbonne, Anne, Blanckaert, Karine, Bajolet, Odile, Bernet, Claude, Verdeil, Xavier, Astagneau, Pascal, Desenclos, Jean-Claude, Nordmann, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291215/
https://www.ncbi.nlm.nih.gov/pubmed/16965700
http://dx.doi.org/10.3201/eid1208.051547
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author Naas, Thierry
Coignard, Bruno
Carbonne, Anne
Blanckaert, Karine
Bajolet, Odile
Bernet, Claude
Verdeil, Xavier
Astagneau, Pascal
Desenclos, Jean-Claude
Nordmann, Patrice
author_facet Naas, Thierry
Coignard, Bruno
Carbonne, Anne
Blanckaert, Karine
Bajolet, Odile
Bernet, Claude
Verdeil, Xavier
Astagneau, Pascal
Desenclos, Jean-Claude
Nordmann, Patrice
author_sort Naas, Thierry
collection PubMed
description VEB-1 extended-spectrum β-lactamase–producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resistance.
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spelling pubmed-32912152012-03-05 VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France Naas, Thierry Coignard, Bruno Carbonne, Anne Blanckaert, Karine Bajolet, Odile Bernet, Claude Verdeil, Xavier Astagneau, Pascal Desenclos, Jean-Claude Nordmann, Patrice Emerg Infect Dis Research VEB-1 extended-spectrum β-lactamase–producing Acinetobacter baumannii was responsible for an outbreak in hospitals in France. A national alert was triggered in September 2003 when 4 hospitals reported clusters of A. baumannii infection with similar susceptibility profiles. Case definitions and laboratory guidelines were disseminated, and prospective surveillance was implemented; strains were sent to a single laboratory for characterization and typing. From April 2003 through June 2004, 53 hospitals reported 290 cases of A. baumannii infection or colonization; 275 isolates were bla(VEB-1)-positive and clonally related. Cases were first reported in 5 districts of northern France, then in 10 other districts in 4 regions. Within a region, interhospital spread was associated with patient transfer. In northern France, investigation and control measures led to a reduction of reported cases after January 2004. The national alert enabled early control of new clusters, demonstrating the usefulness of early warning about antimicrobial drug resistance. Centers for Disease Control and Prevention 2006-08 /pmc/articles/PMC3291215/ /pubmed/16965700 http://dx.doi.org/10.3201/eid1208.051547 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Naas, Thierry
Coignard, Bruno
Carbonne, Anne
Blanckaert, Karine
Bajolet, Odile
Bernet, Claude
Verdeil, Xavier
Astagneau, Pascal
Desenclos, Jean-Claude
Nordmann, Patrice
VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France
title VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France
title_full VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France
title_fullStr VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France
title_full_unstemmed VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France
title_short VEB-1 Extended-Spectrum β-lactamase–producing Acinetobacter baumannii, France
title_sort veb-1 extended-spectrum β-lactamase–producing acinetobacter baumannii, france
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291215/
https://www.ncbi.nlm.nih.gov/pubmed/16965700
http://dx.doi.org/10.3201/eid1208.051547
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