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Loss-of-Function Screen Reveals Novel Regulators Required for Drosophila Germline Stem Cell Self-Renewal

The germline stem cells (GSCs) of Drosophila melanogaster ovary provide an excellent model system to study the molecular mechanisms of stem cell self-renewal. To reveal novel factors required for Drosophila female GSC maintenance and/or division, we performed a loss-of-function screen in GSCs by usi...

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Detalles Bibliográficos
Autores principales: Xing, Yalan, Kurtz, Irina, Thuparani, Manisha, Legard, Jillian, Ruohola-Baker, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291504/
https://www.ncbi.nlm.nih.gov/pubmed/22413088
http://dx.doi.org/10.1534/g3.111.001651