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BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution

BTN1, the yeast homolog to human CLN3 (which is defective in Batten disease), has been implicated in the regulation of vacuolar pH, potentially by modulating vacuolar-type H(+)-ATPase (V-ATPase) activity. However, we report that Btn1p and the V-ATPase complex do not physically interact, suggesting t...

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Detalles Bibliográficos
Autores principales: Padilla-López, Sergio, Langager, Deanna, Chan, Chun-Hung, Pearce, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291640/
https://www.ncbi.nlm.nih.gov/pubmed/22107873
http://dx.doi.org/10.1242/dmm.008490

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