Metformin differentially activates ER stress signaling pathways without inducing apoptosis

Endoplasmic reticulum stress signaling (ERSS) plays an important role in the pathogenesis of diabetes and heart disease. The latter is a common comorbidity of diabetes and worsens patient outcome. Results from clinical studies suggest beneficial effects of metformin – a widely used oral drug for the...

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Detalles Bibliográficos
Autores principales: Quentin, Thomas, Steinmetz, Michael, Poppe, Andrea, Thoms, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291647/
https://www.ncbi.nlm.nih.gov/pubmed/22107872
http://dx.doi.org/10.1242/dmm.008110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291647/
https://www.ncbi.nlm.nih.gov/pubmed/22107872
http://dx.doi.org/10.1242/dmm.008110

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