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A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection
The innate immune response provides the first line of defense against viruses and other pathogens by responding to specific microbial molecules. Influenza A virus (IAV) produces double-stranded RNA as an intermediate during the replication life cycle, which activates the intracellular pathogen recog...
Autores principales: | Maelfait, Jonathan, Roose, Kenny, Bogaert, Pieter, Sze, Mozes, Saelens, Xavier, Pasparakis, Manolis, Carpentier, Isabelle, van Loo, Geert, Beyaert, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291650/ https://www.ncbi.nlm.nih.gov/pubmed/22396652 http://dx.doi.org/10.1371/journal.ppat.1002570 |
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