Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and Ubiquitylation

Aberrant expression of Aurora A kinase has been frequently implicated in many cancers and contributes to chromosome instability and phosphorylation-mediated ubiquitylation and degradation of p53 for tumorigenesis. Previous studies showed that p53 is degraded by Kaposi's sarcoma herpesvirus (KSH...

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Detalles Bibliográficos
Autores principales: Cai, Qiliang, Xiao, Bingyi, Si, Huaxin, Cervini, Amanda, Gao, Jianming, Lu, Jie, Upadhyay, Santosh K., Verma, Suhbash C., Robertson, Erle S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291660/
https://www.ncbi.nlm.nih.gov/pubmed/22396649
http://dx.doi.org/10.1371/journal.ppat.1002566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291660/
https://www.ncbi.nlm.nih.gov/pubmed/22396649
http://dx.doi.org/10.1371/journal.ppat.1002566

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