PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

Activating mutations in the RAS family or BRAF frequently occur in many types of human cancers but are rarely detected in breast tumors. However, activation of the RAS-RAF-MEK-ERK Mitogen-Activated Protein Kinase (MAPK) pathway is commonly observed in human breast cancers, suggesting that other gene...

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Detalles Bibliográficos
Autores principales: Shrestha, Yashaswi, Schafer, Eric J., Boehm, Jesse S., Thomas, Sapana R., He, Frank, Du, Jinyan, Wang, Shumei, Barretina, Jordi, Weir, Barbara A., Zhao, Jean J., Polyak, Kornelia, Golub, Todd R., Beroukhim, Rameen, Hahn, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291810/
https://www.ncbi.nlm.nih.gov/pubmed/22105362
http://dx.doi.org/10.1038/onc.2011.515

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