Swainsonine Activates Mitochondria-mediated Apoptotic Pathway in Human Lung Cancer A549 Cells and Retards the Growth of Lung Cancer Xenografts

Swainsonine (1, 2, 8-trihyroxyindolizidine, SW), a natural alkaloid, has been reported to exhibit anti-cancer activity on several mouse models of human cancer and human cancers in vivo. However, the mechanisms of SW-mediated tumor regression are not clear. In this study, we investigated the effects...

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Detalles Bibliográficos
Autores principales: Li, Zhaocai, Xu, Xingang, Huang, Yong, Ding, Li, Wang, Zhisheng, Yu, Gaoshui, Xu, Dan, Li, Wei, Tong, Dewen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291856/
https://www.ncbi.nlm.nih.gov/pubmed/22393311
http://dx.doi.org/10.7150/ijbs.3882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291856/
https://www.ncbi.nlm.nih.gov/pubmed/22393311
http://dx.doi.org/10.7150/ijbs.3882

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