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The role of microRNA-binding site polymorphisms in DNA repair genes as risk factors for bladder cancer and breast cancer and their impact on radiotherapy outcomes

MicroRNAs (miRNAs) are involved in post-transcriptional regulation of gene expression through binding to messenger RNAs (mRNA) thereby promoting mRNA degradation or altered translation. A single-nucleotide polymorphism (SNP) located within a miRNA-binding site could thus alter mRNA translation and i...

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Detalles Bibliográficos
Autores principales: Teo, Mark T.W., Landi, Debora, Taylor, Claire F., Elliott, Faye, Vaslin, Laurence, Cox, David G., Hall, Janet, Landi, Stefano, Bishop, D.Timothy, Kiltie, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291859/
https://www.ncbi.nlm.nih.gov/pubmed/22166496
http://dx.doi.org/10.1093/carcin/bgr300

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