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An Overview of Recent Strategies in Pathogen Sensing
Pathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291922/ https://www.ncbi.nlm.nih.gov/pubmed/22408537 http://dx.doi.org/10.3390/s90604483 |
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author | Heo, Jinseok Hua, Susan Z. |
author_facet | Heo, Jinseok Hua, Susan Z. |
author_sort | Heo, Jinseok |
collection | PubMed |
description | Pathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue to researchers. Although confirmative for the identification of bacteria, conventional methods require time-consuming process involving either the test of characteristic metabolites or cellular reproductive cycles. In this paper, we review recent sensing strategies based on micro- and nano-fabrication technology. These technologies allow for a great improvement of detection limit, therefore, reduce the time required for sample preparation. The paper will be focused on newly developed nano- and micro-scaled biosensors, novel sensing modalities utilizing microfluidic lab-on-a-chip, and array technology for the detection of pathogenic bacteria. |
format | Online Article Text |
id | pubmed-3291922 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-32919222012-03-09 An Overview of Recent Strategies in Pathogen Sensing Heo, Jinseok Hua, Susan Z. Sensors (Basel) Review Pathogenic bacteria are one of the major concerns in food industries and water treatment facilities because of their rapid growth and deleterious effects on human health. The development of fast and accurate detection and identification systems for bacterial strains has long been an important issue to researchers. Although confirmative for the identification of bacteria, conventional methods require time-consuming process involving either the test of characteristic metabolites or cellular reproductive cycles. In this paper, we review recent sensing strategies based on micro- and nano-fabrication technology. These technologies allow for a great improvement of detection limit, therefore, reduce the time required for sample preparation. The paper will be focused on newly developed nano- and micro-scaled biosensors, novel sensing modalities utilizing microfluidic lab-on-a-chip, and array technology for the detection of pathogenic bacteria. Molecular Diversity Preservation International (MDPI) 2009-06-08 /pmc/articles/PMC3291922/ /pubmed/22408537 http://dx.doi.org/10.3390/s90604483 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Heo, Jinseok Hua, Susan Z. An Overview of Recent Strategies in Pathogen Sensing |
title | An Overview of Recent Strategies in Pathogen Sensing |
title_full | An Overview of Recent Strategies in Pathogen Sensing |
title_fullStr | An Overview of Recent Strategies in Pathogen Sensing |
title_full_unstemmed | An Overview of Recent Strategies in Pathogen Sensing |
title_short | An Overview of Recent Strategies in Pathogen Sensing |
title_sort | overview of recent strategies in pathogen sensing |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291922/ https://www.ncbi.nlm.nih.gov/pubmed/22408537 http://dx.doi.org/10.3390/s90604483 |
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