Cargando…

Olmesartan Attenuates the Impairment of Endothelial Cells Induced by Oxidized Low Density Lipoprotein through Downregulating Expression of LOX-1

Oxidized low density lipoprotein (ox-LDL) and its receptor, lectin-Like ox-LDL receptor-1 (LOX-1), play important roles in the development of endothelial injuries. Olmesartan can protect endothelial cells from the impairment caused by various pathological stimulations. In the present study we invest...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hua, Ma, Genshan, Yao, Yuyu, Qian, Huidong, Li, Weizhang, Chen, Xinjun, Jiang, Wenlong, Zheng, Ruolong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291974/ https://www.ncbi.nlm.nih.gov/pubmed/22408405 http://dx.doi.org/10.3390/ijms13021512

Ejemplares similares

Elevated serum FGF21 predicts the major adverse cardiovascular events in STEMI patients after emergency percutaneous coronary intervention
por: Gu, Lingyun, et al.
Publicado: (2021)

Evidence-based study on antithrombotic therapy in patients at risk of a stroke with paroxysmal atrial fibrillation
por: CHEN, XINJUN, et al.
Publicado: (2013)

High-Density Lipoprotein Prevents Endoplasmic Reticulum Stress-Induced Downregulation of Liver LOX-1 Expression
por: Hong, Dan, et al.
Publicado: (2015)

Native and Oxidized Low-Density Lipoproteins Increase the Expression of the LDL Receptor and the LOX-1 Receptor, Respectively, in Arterial Endothelial Cells
por: Catar, Rusan, et al.
Publicado: (2022)

Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein
por: Thakkar, Shraddha, et al.
Publicado: (2015)

Electronegative Low-Density Lipoprotein Increases C-Reactive Protein Expression in Vascular Endothelial Cells through the LOX-1 Receptor
por: Chu, Chih-Sheng, et al.
Publicado: (2013)

Impaired lipophagy in endothelial cells with prolonged exposure to oxidized low-density lipoprotein
por: Zhang, Cai-Ping, et al.
Publicado: (2020)

Oxidized low-density lipoprotein stimulates dendritic cells maturation via LOX-1-mediated MAPK/NF-κB pathway
por: Huang, D., et al.
Publicado: (2021)

Proteolytic Regulation of the Lectin-Like Oxidized Lipoprotein Receptor LOX-1
por: Mentrup, Torben, et al.
Publicado: (2021)

Role of LOX-1 and ROS in oxidized low-density lipoprotein induced epithelial-mesenchymal transition of NRK52E
por: Wang, Rui, et al.
Publicado: (2010)

The triglycerides-glucose index and the triglycerides to high-density lipoprotein cholesterol ratio are both effective predictors of in-hospital death in non-diabetic patients with AMI
por: Guo, Jiaqi, et al.
Publicado: (2022)

Rapamycin Inhibits Oxidized Low Density Lipoprotein Uptake in Human Umbilical Vein Endothelial Cells via mTOR/NF-κB/LOX-1 Pathway
por: Zhou, Yan-De, et al.
Publicado: (2016)

Mannose-Binding Lectin Reduces Oxidized Low-Density Lipoprotein Induced Vascular Endothelial Cells Injury by Inhibiting LOX1-ox-LDL Binding and Modulating Autophagy
por: Zhou, Xuelian, et al.
Publicado: (2023)

Electronegative Low-Density Lipoprotein L5 Impairs Viability and NGF-Induced Neuronal Differentiation of PC12 Cells via LOX-1
por: Wang, Jiz-Yuh, et al.
Publicado: (2017)

Downregulation of low-density lipoprotein receptor mRNA in lymphatic endothelial cells impairs lymphatic function through changes in intracellular lipids
por: Vachon, Laurent, et al.
Publicado: (2022)

Oxidized Low-Density Lipoprotein-Deteriorated Psoriasis Is Associated with the Upregulation of Lox-1 Receptor and Il-23 Expression In Vivo and In Vitro
por: Shih, Chun-Ming, et al.
Publicado: (2018)

Salidroside downregulates microRNA-133a and inhibits endothelial cell apoptosis induced by oxidized low-density lipoprotein
por: Zhang, Yongjie, et al.
Publicado: (2020)

The Role of High-Density Lipoproteins in Endothelial Cell Metabolism and Diabetes-Impaired Angiogenesis
por: Primer, Khalia R., et al.
Publicado: (2020)

Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomes
por: Pimenta, Eduardo, et al.
Publicado: (2010)

Protein disulfide-isomerase A3 knockdown attenuates oxidized low-density lipoprotein-induced oxidative stress, inflammation and endothelial dysfunction in human umbilical vein endothelial cells by downregulating activating transcription factor 2
por: Jia, Jing, et al.
Publicado: (2022)

High-density lipoproteins attenuate high glucose-impaired endothelial cell signaling and functions: potential implications for improved vascular repair in diabetes
por: Chen, Xing, et al.
Publicado: (2017)

Liraglutide ameliorates oxidized LDL-induced endothelial dysfunction by GLP-1R-dependent downregulation of LOX-1-mediated oxidative stress and inflammation
por: Ying, Wu, et al.
Publicado: (2023)

Effect of angiotensin receptor blockade on endothelial function: focus on olmesartan medoxomil
por: Ferrario, Carlos
Publicado: (2009)

Effects of Olmesartan on Endothelial Progenitor Cell Mobilization and Function in Carotid Atherosclerosis
por: Gong, Xin, et al.
Publicado: (2015)

Oxidized low‐density lipoprotein activates extracellular signal‐regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells
por: Zhang, Qi, et al.
Publicado: (2021)

Chronic Aerobic Exercise Decreases Lectin-Like Low Density Lipoprotein (LOX-1) Receptor Expression in Heart of Diabetic Rat
por: Riahi, Simin, et al.
Publicado: (2016)

Human electronegative low-density lipoprotein modulates cardiac repolarization via LOX-1-mediated alteration of sarcolemmal ion channels
por: Lee, An-Sheng, et al.
Publicado: (2017)

Enteropathy Associated with Olmesartan
por: Silva, Bruno Moreira da, et al.
Publicado: (2015)

Hyperoside inhibits the effects induced by oxidized low-density lipoprotein in vascular smooth muscle cells via oxLDL-LOX-1-ERK pathway
por: Zhang, Zhengyu, et al.
Publicado: (2017)

Serum Soluble Lectin-like Oxidized Low-Density Lipoprotein Receptor-1 (sLOX-1) Is Associated with Atherosclerosis Severity in Coronary Artery Disease
por: Kott, Katharine A., et al.
Publicado: (2023)

Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
por: Abdo, Adrian I., et al.
Publicado: (2017)

Olmesartan Attenuates Tacrolimus-Induced Biochemical and Ultrastructural Changes in Rat Kidney Tissue
por: Al-Harbi, Naif O., et al.
Publicado: (2014)

Olmesartan attenuates pressure-overload- or post-infarction-induced cardiac remodeling in mice
por: Wang, Qiancheng, et al.
Publicado: (2017)

Salidroside attenuates oxidized low-density lipoprotein-induced endothelial cell injury via promotion of the AMPK/SIRT1 pathway
por: Zhao, Dongming, et al.
Publicado: (2019)

Olmesartan/amlodipine vs olmesartan/hydrochlorothiazide in hypertensive patients with metabolic syndrome: the OLAS study
por: Martinez-Martin, F J, et al.
Publicado: (2011)

Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2(loxP/loxP) Villin-Cre mice
por: Kortüm, Benedikt, et al.
Publicado: (2015)

Oxidized low density lipoprotein inhibits the migration of aortic endothelial cells in vitro
Publicado: (1993)

Ticagrelor suppresses oxidized low-density lipoprotein-induced endothelial cell apoptosis and alleviates atherosclerosis in ApoE(−/−) mice via downregulation of PCSK9
por: Xia, Xiaodong, et al.
Publicado: (2019)

Olmesartan: Induced maculopapular rash
por: Bhushan, Aruna, et al.
Publicado: (2013)

Enteropatía secundaria a olmesartán
por: Curieses Luengo, María, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_a1ejmm6ucbtad39g5k01l4ruo3